Project description:We used microarrays to identify genes implicated in breast cancer progression Experiment Overall Design: By serially transplanting initial carcinogen induced rat mammary tumors (PR for primary tumor) through five generations of syngeneic hosts, we generated a series of tumors (T1 through T5) with varying invasive and metastatic phenoytpes
Project description:Fish oil alters tamoxifen-modulated expression of genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors
Project description:In order to establish a rat embryonic stem cell transcriptome, mRNA from rESC cell line DAc8, the first male germline competent rat ESC line to be described and the first to be used to generate a knockout rat model was characterized using RNA sequencing (RNA-seq) analysis.
