Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

BL-HiC analysis of water avoidance stressed BALB/c mice colon epithelial cells

ABSTRACT: BL-HiC analysis of water avoidance stressed BALB/c mice colon epithelial cells

PROVIDER: PRJNA977227 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR24757803_1.fastq.gz	Fastqsanger.gz
	SRR24757803_2.fastq.gz	Fastqsanger.gz
	SRR24757804_1.fastq.gz	Fastqsanger.gz
	SRR24757804_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 9

Similar Datasets

BL-HiC analysis of water avoidance stressed BALB/c mice colon epithelial cells

Project description:We profiled emotional stress caused chromatin structure changes in colon epithelial cells from BALB/c mice.

2023-07-10 | GSE233649 | GEO

Transcriptome analysis of the kidney of socially stressed male C57 BL/6 mice

Project description:To investigate the difference of gene expression between kidneys of groups with different treatments, We performed gene expression profiling analysis using data obtained from RNA-seq of kidney from socially stressed male C57 BL/6 mice with different treatments.

2023-09-15 | GSE207710 | GEO

Transcriptome analysis of the kidney of socially stressed male C57 BL/6 mice

Project description:Transcriptome analysis of the kidney of socially stressed male C57 BL/6 mice

| PRJNA856864 | ENA

Fusobacterium necrophorum BL strain:BL

Project description:Fusobacterium necrophorum BL strain:BL Genome sequencing and assembly

| PRJNA232676 | ENA

RNA seq analysis of BL/6C57 or BL/6NZB mice

Project description:RNA seq analysis was done on the liver samples of BL/6C57 or BL/6NZB male and female mice at 50 weeks

2021-12-15 | GSE190767 | GEO

Transcription profiling of hippocampus samples from the Rattus norvegicus Syracuse High Avoidance (SHA) and Syracuse Low Avoidance (SLA) strains

Project description:Comparisons of hippocampi of Syracuse High Avoidance (SHA) and Syracuse Low Avoidance (SLA) learning rats

2007-10-12 | E-GEOD-932 | biostudies-arrayexpress

Syracuse High/Low Avoidance Learning in Rats

Project description:Comparisons of hippocampi of Syracuse High Avoidance (SHA) and Syracuse Low Avoidance (SLA) learning rats Keywords: other

2003-12-31 | GSE932 | GEO

Lyngbya aestuarii BL J strain:BL J

Project description:Lyngbya aestuarii BL J strain:BL J Genome sequencing and assembly

| PRJNA208960 | ENA

C42B HiC

Project description:C42B HiC

| PRJNA843050 | ENA

Selective enhancement and repression of glucocorticoid receptor signaling by coregulator Hic-5

Project description:The glucocorticoid receptor (GR) recruits many coregulators via the well characterized AF2 interaction surface in the GR ligand binding domain, but LIM domain coregulator Hic-5 binds to the relatively uncharacterized tau2 activation domain in the hinge region of GR. Requirement of Hic-5 for glucocorticoid-regulated gene expression in U2OS osteosarcoma cells was defined by Hic-5 depletion and global gene expression analysis. Hic-5 depletion had selective and dramatic effects, positive and negative, on both activation and repression of GR target genes. For some hormone-induced genes, Hic-5 facilitated recruitment of the Mediator complex and RNA polymerase II. In contrast, many genes were not regulated by hormone until Hic-5 was depleted. On these genes Hic-5 acted at a very early step of the regulatory process, preventing efficient GR binding on enhancers, chromatin remodeling, and thus preventing glucocorticoid-driven transcriptional regulation. Overall, Hic-5 has selective and diverse roles on GR target genes, functioning as coactivator on some genes and corepressor on others, and either facilitating or opposing the glucocorticoid-driven actions of GR. Hic-5 exhibits multiple mechanisms of action, either regulating GR binding to DNA and chromatin remodeling, or facilitating later steps in transcription complex assembly. We investigate the relationship between GR and Hic5 and identify classes of genes that respond differently when cells are induced with hormone and when Hic5 is knocked down We knock down Hic-5 (TGFB1I1) in U2OS cells using siRNA (siHic5_2) along with nonspecific siRNA (shNS) and assay gene expression changes at 4 different time points of hormone treatment. We also include non-infected control (NI) as a second control at each time point.

2014-03-21 | E-GEOD-46448 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data