Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ScRNA-seq analysis of human peripheral blood mononuclear cells collected at the acute HIV-1 infection timepoint

ABSTRACT: scRNA-seq analysis of human peripheral blood mononuclear cells collected at the acute HIV-1 infection timepoint

PROVIDER: PRJNA977691 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR24767500.fastq.gz	Fastqsanger.gz
	SRR24767501.fastq.gz	Fastqsanger.gz
	SRR24767502.fastq.gz	Fastqsanger.gz
	SRR24767503.fastq.gz	Fastqsanger.gz
	SRR24767504.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 184

Similar Datasets

scRNA-seq analyses of HTO-tagged human peripheral blood mononuclear cells collected at the ART timepoint during HIV-1 disease

Project description:scRNA-seq analyses of HTO-tagged human peripheral blood mononuclear cells collected at the ART timepoint during HIV-1 disease

| PRJNA1078068 | ENA

scRNA-seq analysis of human peripheral blood mononuclear cells collected at the acute HIV-1 infection timepoint

Project description:To identify host factors associated with HIV-1 control during acute infection, single cell gene expression profiles of immune cells were examined

2023-12-14 | GSE233747 | GEO

scRNA-seq analyses of HTO-tagged human peripheral blood mononuclear cells collected at the ART timepoint during HIV-1 disease

Project description:We investigated if differences in host gene expression modulate the size of the total HIV-1 PBMC reservoir during suppressive ART. Individuals treated with ART during acute infection who demonstrated effective viral suppression but varying frequencies of HIV-1 DNA+ cells were characterized by single-cell RNA sequencing (scRNA-seq). Differentially expressed genes and enriched pathways demonstrated increased monocyte activity in participants with undetectable HIV-1 reservoirs. This was validated in an independent study cohort comprised of 38 participants with different genetic backgrounds and HIV-1 subtype infections.

2025-01-29 | GSE256089 | GEO

Profiling of peripheral blood mononuclear cells from HIV-1-infected elite suppressors, viremic patients, and uninfected control donors

Project description:This SuperSeries is composed of the following subset Series: GSE33387: NanoString miRNA profiling of peripheral blood mononuclear cells from HIV-1-infected elite suppressors, viremic patients, and uninfected control donors GSE33492: TaqMan Peripheral blood mononuclear cell miRNA profiles of HIV-1-infected elite suppressors, viremic patients, and uninfected control donors Refer to individual Series

2012-02-22 | E-GEOD-33617 | biostudies-arrayexpress

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

Project description:This SuperSeries is composed of the following subset Series: GSE33837: Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1) [miRNA] GSE33877: Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1) [mRNA] Refer to individual Series

2011-11-23 | E-GEOD-33879 | biostudies-arrayexpress

Transcription profiling of peripheral blood mononuclear cells from HIV-infected patients selected according to their viral load

Project description:Gene expression profile was performed on peripheral blood mononuclear cells from HIV-infected patients selected in a cross-sectional analysis according to their viral load.

2004-01-09 | E-MEXP-53 | biostudies-arrayexpress

Transcription profiling of chromosome 22 genes in human peripheral blood mononuclear cells after stimulation with HIV-gag and env peptides

Project description:Comparison of expression levels of the genes on chromosome 22 in the peripheral blood mononuclear cells at various time points after stimulation with HIV-gag and env peptides

2008-10-31 | E-TABM-571 | biostudies-arrayexpress

Expression data from primary human leukocytes (peropheral blood mononuclear cells, PBMC) cultured in vitro with HIV-1MN, HIV-2NIH-Z, CpG-A ODN or media alone

Project description:HIV-1 and HIV-2 can both infect humans, but HIV-2 causes a slow progressing disease and is well controlled by the immune system for prolonged period of times. Here we tested acute response aainst HIV-1 and HIV-2 exposure in peripheral blood mononuclear cells (PBMC) from three indepednent donors.

2014-07-02 | GSE58994 | GEO

Peripheral blood genetic signature of severe cirrhosis in HIV/HCV coinfected patients

Project description:PolyA-RNA sequencing on Peripheral Blood Mononuclear Cells of HIV/HCV coinfected patients with different cirrhosis states.

2023-02-28 | E-MTAB-12251 | biostudies-arrayexpress

Gene expression profiles of peripheral blood mononuclear cells from HIV and HCV coinfected patients before and after 24 weeks of combined antiretroviral therapy.

Project description:We aim to characterize HIV and HCV coinfected patient response to combined antiretroviral therapy through genome-wide expression profiling of patients' periperhal blood mononuclear cells before and after treatment initiation (baseline and 24 weeks). Individuals with frank cirrhosis were excluded from the study. We used Affymetrix PrimeView arrays to quantify baseline transcriptomic characteristics and changes in the transcriptome following treatment. Gene expression changes were analyzed based on the change in expression of each transcript per patient. Mononuclear cells were purified from peripheral blood samples of 8 patients with HIV and HCV coinfection at baseline and after 24 weeks of combined antiretroviral therapy. Genes from whole blood RNA was measured via Affymetrix PrimeView microarrays.

2014-10-07 | E-GEOD-56619 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data