Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Expression data from 18h-fasted WT versus KLF15-null mice: liver and quadriceps skeletal muscle

OTHER RELATED OMICS DATASETS IN: E-GEOD-7137

PROVIDER: PRJNA98205 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of mouse livers and quadriceps muscles of Kruppel-like factor 15 (KLF15) null mutants after an overnight fast to provide insight into the role of KLF15 in gluconeogenesis

Project description:We used microarray analysis to identify differences in gene expression levels, in liver and in quadriceps skeletal muscle, between 18h (overnight) fasted WT control and Kruppel-like factor 15 (KLF15)-null mice. Experiment Overall Design: Liver and skeletal muscle (quadriceps) tissues were isolated from 4-5 month old, 18h-fasted WT and KLF15-null female mice for RNA extraction and hybridization on Affymetrix microarrays.

2007-11-07 | E-GEOD-7137 | biostudies-arrayexpress

Expression data from 18h-fasted WT versus KLF15-null mice: liver and quadriceps skeletal muscle

2007-04-02 | GSE7137 | GEO

Expression data from 18h-fasted WT versus KLF15-null mice: heart

Project description:We used microarray analysis to identify differences in gene expression levels in heart following an 18h (overnight) fast in WT control and KLF15-null mice Heart tissue was isolated from 3-4 month old, 18h-fasted WT and KLF15-null male mice for RNA extraction and hydridization on Affymetrix microarrays

2014-01-09 | E-GEOD-53231 | biostudies-arrayexpress

Mus musculus

Project description:Expression data from 18h-fasted WT versus KLF15-null mice: heart

| PRJNA231177 | ENA

Transcriptional effects of KLF15 deletion in quadriceps muscle

Project description:We report bulk RNA-sequencing of quadriceps muscle harvested from MyoCre and skeletal muscle specific KLF15 (K15-SKO) mice

2021-02-17 | GSE160877 | GEO

Global quadriceps skeletal muscle transcript data from fasted male BXD strains on chow or high fat diet

2014-09-26 | GSE60151 | GEO

Expression data from 18h-fasted WT versus KLF15-null mice: heart

Project description:We used microarray analysis to identify differences in gene expression levels in heart following an 18h (overnight) fast in WT control and KLF15-null mice

2014-01-09 | GSE53231 | GEO

Global quadriceps skeletal muscle transcript data from fasted male BXD strains on chow or high fat diet

Project description:Transcript data from quadriceps skeletal muscle from fasted-state male BXD strains on Quadriceps, Chow or Quadriceps, High fat diet We used microarrays to compare the skeletal muscle expression differences across males in the BXD strain family and across two diverse diets 29-week-old male mice were fasted overnight (6pm-9am), anesthetized under isoflurane, and perfused, then quadriceps were snap-frozen in liquid nitrogen for RNA extraction and RNEasy cleanup. Each dietary and strain cohort consisted of ~5 animals which were prepared independently then pooled evenly by M-BM-5g RNA before the Affymetrix arrays were run.

2014-09-26 | E-GEOD-60151 | biostudies-arrayexpress

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse (NMR assay)

Project description:Regulation between the fed and fasted state in mammals is partially controlled by peroxisome proliferator activated receptor-alpha (PPAR-alpha). Expression of the receptor is high in liver, heart and skeletal muscle, but decreases with age. A combined 1H NMR spectroscopy and GC-MS metabolomic approach has been used to examine metabolism in liver, heart, skeletal muscle and adipose tissue in PPAR-alpha null mice and wild type controls during ageing between 3-13 months. For the PPAR-alpha-null mouse multivariate statistics highlighted hepatic steatosis, reductions in the concentrations of glucose and glycogen in both liver and muscle tissue, and profound changes in lipid metabolism in each tissue, reflecting known expression targets of the PPAR-alpha receptor. Hepatic glycogen and glucose also decreased with age for both genotypes. These findings indicate the development of age related hepatic steatosis in the PPAR-alpha-null mouse, with the normal metabolic changes associated with ageing exacerbating changes associated with genotype. Furthermore, the combined metabolomic and multivariate statistics approach provides a robust method for examining the interaction between age and genotype. </p> The GC-MS assay for this study can be found in the MetaboLights study MTBLS314.

2018-10-11 | MTBLS261 | MetaboLights

mRNA Expression Changes with Cofilin-2 Deficiency

Project description:mRNA Expression in Quadriceps Muscle from Cofilin-2 Null Mice Compared to WT Littermates on Day 7

2015-09-01 | GSE61404 | GEO