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Knockdown TIMM13 in A549 lung cancer cell line

ABSTRACT: Knockdown TIMM13 in A549 lung cancer cell line

PROVIDER: PRJNA983127 | ENA |

REPOSITORIES: ENA

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Human lung cancer cell line A549 +/- CD43 knockdown

Project description:Human lung cancer cell line A549 +/- CD43 knockdown

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Knockdown TIMM13 in A549 lung cancer cell line

Project description:We depleted TIMM13 using short interfering RNA (siRNA) in A549 lung cancer cells, and found that silencing of TIMM13 could significantly inhibit A549 cell proliferation. Thus, we conducted RNA-seq in the A549 cells transduced with either nontargeting siRNA or two distinct TIMM13-specific siRNAs. We observed widespread gene expression change in A549 cells upon TIMM13 knockdown.

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