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Red blood cells-heme-exposure and tumor-associated macrophage identity

ABSTRACT: Red blood cells-heme-exposure and tumor-associated macrophage identity

PROVIDER: PRJNA993993 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR25243572.fastq.gz	Fastqsanger.gz
	SRR25243573.fastq.gz	Fastqsanger.gz

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Investigation of Bach2 function by heme-iron homeostasis in red-pulp macrophage.

Project description:Macrophages are central in regulating iron homeostasis. Transcription repressor Bach2 regulates by heme. Here we investigated the relationship between heme-regulated Bach2 and macrophage in spleen. We found that gene expression were not many change between WT and Bach2 knock out mice in red-pulp macrophage.Our results suggest that the function of the red-pulp macrophage is not dependent on according to expression of Bach2.

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Red blood cells-heme-exposure and tumor-associated macrophage identity

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