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ProteomicsProteomics-based identification of SIRT2 interaction partners
The NAD+ dependent deacetylase enzyme SIRT2 functions in diverse cellular processes including the cell cycle, metabolism and has recently been demonstrated to have important roles during tumorigenesis and bacterial infection. Though predominantly localised in the cytoplasm SIRT2 has been shown to con...
ORGANISM(S): Homo Sapiens (human) 
2020-02-20 | PXD011523 | Pride
Bacterial infection Ap-ms Nuclear translocation Sirt2 Tumorigenesis 
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ProteomicsA quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering the mechanisms underlying diseases such as cancer. To enable the in-depth analysis of protein interactions in chromatin-associated protein complexes, we have previously developed a meth...
ORGANISM(S): Homo Sapiens (human) 
2018-06-08 | PXD007968 | Pride
Patient derived xenografts (pdx) Clinical samples Isobaric labelling Interactome Proteomics 4-hydrotamoxifen Rime Breast cancer Qplex-rime Tmt Estrogen receptor alpha 
1K
OtherCRUKCI
Organisation EGAO00000000612
EGAO00000000612 | EGA
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GenomicsICGC Oesophageal Adenocarcinoma sequence data - fc_paper_dna_release - samples
Data supporting: "Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma." Mourikis et al. WGS (BAM files) 521 samples
EGAD00001004775 | EGA
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GenomicsICGC Oesophageal Adenocarcinoma sequence data - mobile_elements - samples
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
EGAD00001001048 | EGA
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GenomicsICGC Oesophageal Adenocarcinoma sequence data - 100 - samples
Samples from the "100" project that are in the ICGC PanCancer project.
EGAD00001001071 | EGA
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GenomicsICGC Oesophageal Adenocarcinoma sequence data - icgc_release_26 - samples
WGS sequencing for 303 cases (620 samples) from the ICGC ESAD-UK project Tumours 50x Normals 30x HiSeq X BAM files These samples are all available in ICGC release 26
EGAD00001003580 | EGA
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GenomicsICGC Oesophageal Adenocarcinoma sequence data - 100_all_samples - samples
All samples from the "100" project
EGAD00001001457 | EGA
0
GenomicsICGC Oesophageal Adenocarcinoma sequence data - dcc_release_28 - samples
WGS sequencing for 409 cases (832 samples) from the ICGC ESAD-UK project Tumours 50x Normals 30x HiSeq X BAM files These samples are all available in ICGC release 28
EGAD00001004137 | EGA
0
GenomicsICGC Oesophageal Adenocarcinoma sequence data - 129_cohort - samples
Sequencing data for ICGC Oesophageal Adenocarcinoma tissue samples - 129_cohort EAC whole genomic sequencing data - Publication Secrier & Li et al., 2016, Nature Genetics
EGAD00001002218 | EGA
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