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ProteomicsPhosphoproteomics evaluation of the effect of GLP-1 on the porcine pacemaker
GLP-1 induces an increase in heart rate, but its mechanism remains elusive. We used a phosphoproteomic approach to evaluate the effect of GLP-1 on the porcine sinus node. Tissue samples from the sinus node region and left ventricle were collected from eight animals following a 60-minute infusion wit...
ORGANISM(S): Sus Scrofa Domesticus (domestic Pig) 
2024-06-10 | PXD042583 | Pride
Heart Porcine Sinus node Phosphoproteomics Glp-1 Pacemaker Glucagon-like peptide 1 Pig 
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GenomicsGENEVA Genes and Environment Initiatives in Type 2 Diabetes (Nurses' Health Study/Health Professionals Follow-up Study)
...dies of women and men for whom stored blood and DNA samples are available as well as detailed information on dietary and lifestyle variables. The major goals of the project include: 1. To conduct a GWA analysis among 3,000 cases of T2D and 3,000 healthy controls in NHS/HPFS cohorts. 2. To use i...
phs000091.v2.p1 | EGA
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GenomicsMulti-Ethnic Study of Atherosclerosis (MESA) Cohort
...of Chinese descent.

Participants were recruited from six field centers across the United States: Wake Forest University, Columbia University, Johns Hopkins University, University of Minnesota, Northwestern University and University of California - Los Angeles. Each participant received an ext...

phs000209.v10.p2 | EGA
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GenomicsGenome wide association study for early onset coronary disease and related phenotypes (ADVANCE)
...erarching goal of the study is to improve our ability to prevent, diagnose and treat CAD. The initial study included recruitment of over 3600 subjects (including 1873 subjects with incident clinically significant coronary disease and 1745 control subjects) from multiple race/ethnic backgrou...
phs000423.v1.p1 | EGA
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GenomicsNHLBI Family Heart Study (FamHS-Visit1 and FamHS-Visit2)
...s later, study participants belonging to the largest pedigrees were invited for a second clinical exam (FamHS Visit 2). A total of 2,756 Caucasian subjects in 508 extended families were examined.

A two-phase design was adopted for the genome wide association (GWA) study. In phase-1, 1007 subje...

phs000221.v1.p1 | EGA
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Genomics,MultiomicsFramingham Cohort
...direction of the National Heart Institute (now known as the National Heart, Lung, and Blood Institute, NHLBI) -- embarked on a novel and ambitious project in health research. At the time, little was known about the general causes of heart disease and stroke, but the death rates for CVD had been incre...
phs000007.v17.p6 | EGA
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GenomicsSTAMPEED: Myocardial Infarction Genetics Consortium (MIGen)

Myocardial infarction (MI) is a common complex disease and the leading cause of death and disability worldwide. The genetic basis of this disease is largely unknown. It has been thought that early-onset MI events would have a substantially greater heritability, thus making DNA collections wit...

phs000294.v1.p1 | EGA
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Genomics,MultiomicsNHLBI Atherosclerosis Risk in Communities (ARIC) Candidate Gene Association Resource (CARe)
...ng and Blood Institute (NHLBI), is a prospective epidemiologic study conducted in four U.S. communities. The four communities are Forsyth County, NC; Jackson, MS; the northwest suburbs of Minneapolis, MN; and Washington County, MD. ARIC is designed to investigate the etiology and natural history of a...
phs000280.v1.p1 | EGA
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Genomics,MultiomicsThe Atherosclerosis Risk in Communities (ARIC) Study
...and Blood Institute (NHLBI), is a prospective epidemiologic study conducted in four U.S. communities. The four communities are Forsyth County, NC; Jackson, MS; the northwest suburbs of Minneapolis, MN; and Washington County, MD. ARIC is designed to investigate the etiology and natural history of...
phs000090.v1.p1 | EGA
0
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
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