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GenomicsTranscriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming (ChIP-seq)
Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engaged at pluripotency promoters in reprogramming but remains pa...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-59828 | biostudies-arrayexpress
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TranscriptomicsGene expression signatures of MEF2D-silencing hepatocellular carcinoma cells
Global expression profiles in Huh7 after infection with Lv-shMEF2D and Lv-scrambled, as well as transfection with siRNA-MEF2D and siRNA-control, were compared to investigate the molecular mechanisms involved in MEF2D-mediated regulation of cell cycle. In order to investigate the molecular mechanisms ...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-37123 | biostudies-arrayexpress
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ProteomicsGPX4 immunoprecipitation in Huh7 cells
Huh7 cells with expression of Flag-GPX4 were treated with IGF1. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Human 
2023-02-22 | MSV000091343 | MassIVE
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