Sort   by:  
 Page size 
0
TranscriptomicsMapping of dsRNA in yeast using reconstituted RNAi pathway
Small RNA produced by Dicer (Dcr1) are used to map dsRNA in wild-type strain and a xrn1-delta mutant of S. cerevisiae, inactivated for the cytoplasmic 5'-3' RNA decay pathway. Small RNA sequencing in wild-type and xrn1-delta strains of S. cerevisiae, with or without reconstituted RNAi pathway.
ORGANISM(S): Saccharomyces cerevisiae 
2015-08-11 | E-GEOD-64090 | biostudies-arrayexpress
0
TranscriptomicsExpression of subtelomeric lncRNAs links telomeres maintenance with RNA decay in S. cerevisiae
Long non-coding RNAs (lncRNAs) have been shown to regulate gene expression, chromatin domains and chromosome stability in eukaryotic cells. Recent observations have reported the existence of telomere associated long ncRNAs (TERRA, telomeric repeat containing RNA) in mammalian and yeast cells but thei...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-30 | E-GEOD-67585 | biostudies-arrayexpress
0
TranscriptomicsRNA processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.
Eukaryotic cells respond to DNA double-strand breaks (DSBs) by activating a checkpoint that depends on the protein kinases Tel1/ATM and Mec1/ATR. Mec1/ATR is activated by RPA-coated single-stranded DNA (ssDNA), which arises upon nucleolytic degradation (resection) of the DSB. Emerging evidences indic...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-20 | E-GEOD-63444 | biostudies-arrayexpress
0
UnknownTGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma
Not available
S-SCDT-10_1038-S44319-024-00075-Z | biostudies-other
0
TranscriptomicsDnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency
We found that Dnmt3l-KO donor cells display decreased levels of H3K9me3 and H3K27me3 accumulation, higher level of active histone mark H3K27ac and increased cytoplasmic localization of HDAC1, implicating a permissive epigenetic state beneficial for nuclear reprogramming. To investigate the gene expre...
ORGANISM(S): Mus musculus 
2015-08-01 | E-GEOD-69007 | biostudies-arrayexpress
Sort   by:  
 Page size