Sort   by:  
 Page size 
0
ProteomicsProteomic analysis of mitochondria from Huntington's Disease patient iPSC-derived neurons
Huntington's disease is caused by an expanded CAG repeat in the huntingtin gene, yeilding a Huntingtin protein with an expanded polyglutamine tract. Patient-derived induced pluripotent stem cells (iPSCs) can help understand disease; however, defining pathological biomarkers in challanging. Here we us...
ORGANISM(S): Homo Sapiens (human) 
2023-02-10 | PXD037526 | Pride
Mitochondria Neurodegeneration Lc-ms/ms Huntington's disease 
0
Metabolomics,MultiomicsAccumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex
Secondary metabolites are involved in the plant stress response. Among these are scopolin and its active form scopoletin, which are coumarin derivatives associated with reactive oxygen species scavenging and pathogen defence. Here we show that in Arabidopsis thaliana, scopolin accumulation can be ind...
2018-02-05 | MTBLS389 | MetaboLights
0
ProteomicsChronic haloperidol treatment leads to an imbalance of synaptic excitation and inhibition of D1-MSN neurons pointing to a slow remodelling process
Schizophrenia is a chronic mental illness that is among the world’s top twenty causes of years lost to disability according to the global burden of disease 2019 (10.1016/S0140-6736(20)30925-9). Positive symptoms, including hallucinations and delusions in schizophrenia, often improved with conventiona...
ORGANISM(S): Mus Musculus (mouse) 
2023-10-24 | PXD038471 | Pride
Proteomics Msn Haloperidol 
0
Genomics,MultiomicsFramingham Cohort

Startup of Framingham Heart Study. Cardiovascular disease (CVD) is the leading cause of death and serious illness in the United States. In 1948, the Framingham Heart Study (FHS) -- under the direction of the National Heart Institute (now known as the National Heart, Lung, and Blood Institut...

phs000007.v17.p6 | EGA
0
Genomics,MultiomicsDiscovery of Non-ETS Gene Fusions in Human Prostate Cancer using Next Generation RNA Sequencing

Half of prostate cancers harbor gene fusions between TMPRSS2 and members of the ETS transcription factor family. To date little is known about the presence of non-ETS fusion events in prostate cancer. We employed next-generation transcriptome sequencing (RNA-Seq) in order to ex...

phs000310.v1.p1 | EGA
0
UnknownEffect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.
Not available
S-EPMC8492020 | biostudies-literature
0
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
0
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
0
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
Sort   by:  
 Page size