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ProteomicsVerticillium dahliae Frq and Frh form a Frq-Frh complex in dependence on arginine 806 (R806) of Frh
...as homologs of the clock genes [Cascant-Lopez et al., 2020], which are well described in Neurospora crassa [Diernfellner et al., 2020]. In N. crassa, frequency (Frq) and the Frq-interacting RNA helicase (Frh) interact and form the Frq-Frh co...
...induction in tomato plants. Strikingly, the FRH^R806H mutant strain grew similar to the FRQ deletion strain, although transcript and protein levels of Frq were not significantly affected by the FRH^R806H mutation when compared with the wild-type. Therefore, we hypothesized that ...
ORGANISM(S): Verticillium Dahliae Jr2 
2023-07-12 | PXD041716 | Pride
Frq-interacting rna helicase Clock proteins Frq Frequency Verticillium dahliae jr2 Frh 
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ProteomicsQuantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells
Reversible protein phosphorylation is one of the most important posttranslational modifications (PTMs) due to its vital role in cellular functions and signaling pathways. Protein phosphorylation is also known to be involved in the regulation of apoptosis. Previously, we have performed a SILAC-based anal...
ORGANISM(S): Homo Sapiens (human) 
2017-05-11 | PXD004415 | Pride
Phosphorylation Phosphoproteomics : apoptosis Mass spectrometry Cisplatin 
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ProteomicsVerticillium dahliae Vta3 promotes ELV1 virulence factor gene expression in xylem sap, but tames Mtf1-mediated late stages of fungus-plant interactions and microsclerotia formation
Verticillium transcription activator of adhesion 3 (Vta3) is required for plant root colonization and pathogenicity of the soil-borne vascular fungus Verticillium dahliae [Bui et al., 2018]. In this study, we discovered that Vta3 contributes to the virulence of V. dahliae on tomato plants by promotin...
ORGANISM(S): Verticillium Dahliae Jr2 
2023-01-18 | PXD039123 | Pride
Verticillium dahliae Mtf1 Vta3 Verticillium transcription activator of adhesion 3 Jr2 Transcription factor Master transcription factor 1 
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ProteomicsThe velvet protein Vel1 controls initial plant root colonization and conidia formation for xylem distribution in Verticillium wilt
Velvet domain proteins coordinate developmental processes and secondary metabolism in fungi. In this study, we characterized the role of all four velvet prot...
...ins included redox-regulating proteins and metabolic enzymes, but also proteins involved in energy metabolism and transport.
ORGANISM(S): Verticillium Dahliae Jr2 
2021-02-23 | PXD021861 | Pride
Verticillium dahliae Plant pathogen Velvet proteins Velvet domain 
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ProteomicsARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans
...t of RNA polymerase II (Pol II). Surprisingly, the absence of ARMC5 caused the accumulation of n...
...le Pol II complex is compromised. This did not lead to generalized Pol II stalling or a generalized decrease in mRNA transcription. I...
ORGANISM(S): Homo Sapiens (human) 
2023-12-06 | PXD047533 | Pride
Folh1 Polr2a-specific e3 Ubiquitin ligase Pol ii pool size Neural tube defects Armc5 Myelomeningocele Cullin 3 12 subunits of pol ii 
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ProteomicsARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans
...t of RNA polymerase II (Pol II). Surprisingly, the absence of ARMC5 caused the accumulation of n...
...le Pol II complex is compromised. This did not lead to generalized Pol II stalling or a generalized decrease in mRNA transcription. I...
ORGANISM(S): Homo Sapiens (human) 
2023-12-06 | PXD047572 | Pride
Folh1 Polr2a-specific e3 Ubiquitin ligase Pol ii pool size Neural tube defects Armc5 Myelomeningocele Cullin 3 12 subunits of pol ii 
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TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been reported ...
ORGANISM(S): Homo sapiens 
2015-07-10 | GSE70279 | GEO
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ProteomicsThe Isotopic Depletion Increases the Spatial Resolution of FPOP Top-Down Analysis.
...ive analytical method for probing protein structure or protein interaction with other bio-molecules. Since the Fast Photochemical Oxidation of Proteins has already shown its essential role in studying biomolecular as-semblies and it was successfully adopted to characterize the interaction of transcripti...
ORGANISM(S): Homo Sapiens (human) 
2024-01-26 | PXD044447 | Pride
Top-down Fast photochemical oxidation of proteins Protein isotope depletion Electron-capture dissociation Foxo4 Multicasi. Mass spectrometry Ire Insulin response element 
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ProteomicsThe Triticale Mature Pollen and Stigma Proteomes – Assembling the Proteins for a Productive Encounter
Triticeae crops are major contributors to global food production and ensuring their capacity to reproduce and generate seeds is critical. However, despite their importance our knowledge of the proteins underlying Triticeae reproduction is severely lacking and this is not only true of pollen and stig...
ORGANISM(S): X Triticosecale 
2023-03-08 | PXD038905 | Pride
Brassica Stigma Proteomics Triticale Triticeae Pollen Itraq Mass spectrometry Pollination 
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MetabolomicsGNPS - hypoglycemic and antibacterial diterpenoids in Eremophila rugosa
Spectral data and metadata for the puplication: "Polypharmacology-Labeled Molecular Networking: An Analytical Technology Workflow for Accel...
... diterpenoids from the roots of Myoporum insulare. Phytochem. Lett. 39, 49-56. [8] Duke, C. C., Duke, R. K., and Tran, V. H. (2018). Medicinal use of serrulatane diterpenes. Available at: https://patents.google.com/patent/US20190282514A1/en
ORGANISM(S): Eremophila Rugosa 
2021-11-24 | MSV000088442 | GNPS
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