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TranscriptomicsAspirin Exposure Reveals Novel Genes Associated with Platelet Function and Cardiovascular Events (outpatient cardiology)
Background: Identifying individuals at heightened cardiovascular risk is a priority for reducing the global burden of cardiovascular disease. Aspirin is widely used to prevent cardiovascular events, though with variable results. Therefore, we hypothesized that aspirin exposure would reveal novel bi...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-38511 | biostudies-arrayexpress
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GenomicsPhase I Clinical Trial Describing the Pharmacogenomics of Aspirin

The study protocol for both cohorts has been previously described (Journal of Thrombosis and Thrombolysis 2012:1-12).

HV1 cohort: Briefly 50 healthy volunteers were exposed to two weeks of 325mg/day aspirin after which whole blood RNA was collected in PAXgene tubes and profiled by microarra...

phs000548.v1.p1 | EGA
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