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Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
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Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
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Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm and the mitochondrial double membrane. Despite these physical barriers we show that somatically acquired mitochondrial-nuclear genome fusion sequences are prese...
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Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
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Purified recombinant PPARγ-Flag and PRMT4-His were used for in vitro methyltransferase assay.We separated purified methylated PPARγ proteins by SDS-PAGE, visualized them by staining with Coomassie blue, protein lanes were cut into pieces about 1 mm3, and followed further destained.
ORGANISM(S): Homo Sapiens 
2022-06-27 | PXD034929 |
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...SI), Hinxton, Cambridge, UK is a not-for-profit research organisation and a world famous Genome Centre dedicated to the sequencing and functional analysis of genomes. The Sanger Institute underpins biological and medical research worldwide through large-scale analysis, focused research and collaborat...
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Wellcome Trust Sanger Institute
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To access Controlled Access ICGC data at the EGA you must first apply for access on the DACO form. Instructions on this process is available from this web site: http://docs.icgc.org/portal/access/
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Data Access Committee EGAC00001000000
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