Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-27973

ABSTRACT: Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

PROVIDER: E-GEOD-27973 | ExpressionAtlas | 2025-01-24

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-27973-analysis-methods.tsv	Tabular
	E-GEOD-27973-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-27973-configuration.xml	Xml
	E-GEOD-27973-percentile-ranks.tsv	Tabular
	E-GEOD-27973.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 74

Similar Datasets

Homo sapiens

Project description:Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

| PRJNA137767 | ENA

Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

Project description:This study was performed to test the hypothesis that cigarette smoke extract would alter the responses of primary cultures of human bronchial epithelial cells to infection with purified human rhinovirus 16. The data show marked alterations in rhinovirus-induced expression profiles of a number of genes in the presence of cigarette smoke extract (CSE). Cultured epithelial cells from each of 4 donors were exposed to medium alone, rhinovirus 16 (RV16) alone, CSE alone, or RV16 in the presence of CSE. After a 24 h incubation gene expression was assessed.

2011-03-15 | E-GEOD-27973 | biostudies-arrayexpress

Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

2011-03-15 | GSE27973 | GEO

E-MEXP-1512

Project description:Transcription profiling of human bronchial epithelial cells following exposure to whole cigarette smoke

2025-01-22 | E-MEXP-1512 | ExpressionAtlas

E-GEOD-61141

Project description:Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus

2025-01-24 | E-GEOD-61141 | ExpressionAtlas

E-TABM-127

Project description:Transcription profiling by array of human bronchial epithelial cells after exposure to cigarette smoke

2025-01-16 | E-TABM-127 | ExpressionAtlas

Regional heterogeneity in response of airway epithelial cells to cigarette smoke

Project description:To investigate the biochemical and genetic alterations that occur in response to cigarette smoke exposure among airway epithelial cells from different sites in the lungs, we performed microarray-based analysis using small airway epithelial cells (SAEC) and normal human bronchial epithelial cells (NHBE) following 24 h of cigarette smoke extract (CSE). In microarray-based analysis, the small airway showed higher susceptibility to CS compared to the large airway, such as enhanced expression of inflammatory-related pathways including the TNF signaling pathway. Among the TNF-related genes, PTGS2, also known as COX-2, showed the greatest difference in expression levels, with higher CSE-induced increments of both mRNA and protein expression in SAEC compared to NHBE.

2018-01-16 | GSE107200 | GEO

E-GEOD-14383

Project description:Transcription profiling by array of human bronchial epithelial cells after treatment with cigarette smoke condensate

2025-01-24 | E-GEOD-14383 | ExpressionAtlas

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response

Project description:To study the effect of cigarette smoke exposure on Sars-Cov2 infection, we directly exposed mucociliary air-liquid interface (ALI) cultures derived from primary human nonsmoker airway basal stem cells (ABSCs) to short term cigarette smoke and infected them with live SARS-CoV-2. We set out to examine the underlying mechanisms governing the increased susceptibility of cigarette smoke exposed ALI cultures to SARS-CoV-2 infection by usingle cell profiling of the cultures, which showed that interferon response genes were induced in SARS-CoV-2 infected airway epithelial cells in ALI cultures but smoking exposure together with SARS-CoV-2 infection reduced the interferon response.

2020-11-17 | GSE161089 | GEO

The Effect of Repeated Whole Cigarette Smoke Challenge on Human Air-Liquid Interface Lung Epithelial Cultures

Project description:Airway epithelial cells are the first cells of the lungs to be exposed to the toxic agents contained within cigarette smoke. Accordingly, the response of these cells to this challenge is of considerable interest in the context of diseases in which cigarette smoke is a major aetiological factor. We used Affymetrix microarrays to study the effects of repeated cigarette smoke challenge on three-dimensional human lung airway epithelial cultures.

2011-08-31 | GSE30660 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data