Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-50241

ABSTRACT: Expression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant

OTHER RELATED OMICS DATASETS IN: PRJNA217332

TISSUE(S): Retina, Whole Organism, Retina With Retinal Pigment Epithelium

PROVIDER: E-GEOD-50241 | ExpressionAtlas | 2015-07-27

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-50241-analysis-methods.tsv	Tabular
	E-GEOD-50241-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-50241-configuration.xml	Xml
	E-GEOD-50241-configuration.xml.beforeQC	Xml
	E-GEOD-50241-percentile-ranks.tsv	Tabular

Items per page:

1 - 5 of 72

Similar Datasets

Danio rerio

Project description:Expression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant

| PRJNA217332 | ENA

Characterization of Anatomical, Macromolecular, and Gene Expression Changes in the Retinal and Retinal Pigmented Epithelium of the nm3342 Mouse: A Potential Model of Serous Retinal Detachment

Project description:To characterize gene expression changes in mice following serous retinal detachments, we employed whole genome microarray expression profiling as a tool to identify genes with the potential effects on the neural retina as well as retinal pigmented epithelium. Total RNA was harvested from nm3342 (mutant) and age-matched wild-type (C57Bl/6J) mice at P30 or P365 for examination using microarray analysis. Retinas and retinal pigmented epithelium was harvested from both age-matched mutant and wild-type mice.

2015-05-16 | E-GEOD-68961 | biostudies-arrayexpress

Danio rerio

Project description:Gene Expression Profiling of Zebrafish Embryonic Retinal Pigment Epithelium in vivo.

| PRJNA96685 | ENA

Gene Expression Analysis of Zebrafish Melanocytes, Iridophores, and Retinal Pigmented Epithelium Reveals Indicators of Biological Function and Developmental Origin

Project description:In order to facilitate understanding of pigment cell biology, we developed a method to concomitantly purify melanocytes, iridophores, and retinal pigmented epithelium from zebrafish, and analyzed their transcriptomes. Comparing expression data from these cell types and whole embryos allowed us to reveal gene expression co-enrichment in melanocytes and retinal pigmented epithelium, as well as in melanocytes and iridophores. We found 214 genes co-enriched in melanocytes and retinal pigmented epithelium, indicating the shared functions of melanin-producing cells. We found 62 genes significantly co-enriched in melanocytes and iridophores, illustrative of their shared developmental origins from the neural crest. This is also the first analysis of the iridophore transcriptome. Gene expression analysis for iridophores revealed extensive enrichment of specific enzymes to coordinate production of their guanine-based reflective pigment. We speculate the coordinated upregulation of specific enzymes from several metabolic pathways recycles the rate-limiting substrate for purine synthesis, phosphoribosyl pyrophosphate, thus constituting a guanine cycle. The purification procedure and expression analysis described here, along with the accompanying transcriptome-wide expression data, provide the first mRNA sequencing data for multiple purified zebrafish pigment cell types, and will be a useful resource for further studies of pigment cell biology. mRNA profiles of zebrafish pigment cells were generated using Illumina GAIIX sequencing

2013-04-26 | E-GEOD-46387 | biostudies-arrayexpress

Characterization of Anatomical, Macromolecular, and Gene Expression Changes in the Retinal and Retinal Pigmented Epithelium of the nm3342 Mouse: A Potential Model of Serous Retinal Detachment

2015-05-16 | GSE68961 | GEO

Expression data of human neuroblastoma cell lines

Project description:Human neuroblatoma cell lines (N=25) and retinal pigmented epithelium cell lines (N=4) were analyzed for gene expression under untreated/baseline growth conditions. Expression profiling and characterization of a set of Neuroblastoma and retinal pigmented epithelium cell lines

2016-02-19 | E-GEOD-78061 | biostudies-arrayexpress

Gene Expression Analysis of Zebrafish Melanocytes, Iridophores, and Retinal Pigmented Epithelium Reveals Indicators of Biological Function and Developmental Origin

2013-04-26 | GSE46387 | GEO

THE IMMUNE RESPONSE MODULATES ZEBRAFISH RETINAL PIGMENT EPITHELIUM REGENERATION [macrophages]

Project description:THE IMMUNE RESPONSE MODULATES ZEBRAFISH RETINAL PIGMENT EPITHELIUM REGENERATION [macrophages]

| PRJNA649262 | ENA

THE IMMUNE RESPONSE MODULATES ZEBRAFISH RETINAL PIGMENT EPITHELIUM REGENERATION [RPE]

Project description:THE IMMUNE RESPONSE MODULATES ZEBRAFISH RETINAL PIGMENT EPITHELIUM REGENERATION [RPE]

| PRJNA649260 | ENA

Microarray of human ARPE-19 cells treated with Cochlin recombinant protein

Project description:Study the gene expression profiling of human retinal pigmented epithelium cell line ARPE-19 treated with or without human recombinant Cochlin protein for 24 hours.

2023-05-05 | E-MTAB-12364 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data