Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-6846

ABSTRACT: Embryonic mouse mammary progenitor cells +/-Sox9

PROVIDER: E-MTAB-6846 | ExpressionAtlas | 2018-09-17

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-6846-analysis-methods.tsv	Tabular
	E-MTAB-6846-analytics.tsv	Tabular
	E-MTAB-6846-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-6846-configuration.xml	Xml
	E-MTAB-6846-g2_g1-mvaPlot.png	Other

Items per page:

1 - 5 of 18

Similar Datasets

Embryonic mouse mammary progenitor cells +/-Sox9

Project description:Embryonic mouse mammary progenitor cells +/-Sox9

| PRJEB27130 | ENA

Embryonic mouse mammary progenitor cells

Project description:Regulation of stem cell function in embryonic mouse mammary progenitor cells

| PRJEB22485 | ENA

Metabolomics Workbench ST000003 - GNPS - Metabolomic analysis of mouse embryonic fibroblasts, embryonic stem cells, and induced pluripotent stem cells

Project description:mouse embryonic fibroblasts, embryonic stem cells, and induced pluripotent stem cells were compared via metabolomic analysis

2018-08-02 | MSV000082680 | GNPS

Cyclin D1, Id2 and Sox9 are upregulated in a lobular competent COMMA Db clonal derivative’ cells compared to a lobular incompetent clone both in vitro, and in vivo

Project description:Understanding underlying mechanisms responsible for the differentiation and stemness of mouse mammary progenitor cells are paramount to understanding the heterogeneity of mammary development and tumorigenesis. Consequently, studies have isolated and characterized mouse mammary progenitor cell lines such as: COMMA-1D, NSP2 and SP3, but have not parsed the various transcriptomes that play a role in progenitor differentiation and mammary gland development.

2018-10-19 | GSE121499 | GEO

Mus musculus

Project description:Transcriptome profiles of mouse mammary stem cells and progenitor cells

| PRJNA205537 | ENA

RNA-seq of embryonic mammary progenitor cell lines (part A)

Project description:RNA-seq of embryonic mammary progenitor cell lines. Embryonic mammary progenitor cell (eMPC) clones were derived from E12.5-stage mammary organs. After microdissection, mammary primordial 3 was cultured on thick basement membrane extract for 4 weeks. After enzymatic dissociation eMPC swere plated and expanded in 2D culture to obtain a pool of eMPCs. eMPC cells were subject to single cell sorting using FACS. Clones were expanded as single-cell derived clones (eMPC1, 2, etc.) to create the eighteen single cell-derived clones described in this study.

2018-11-30 | E-MTAB-6856 | biostudies-arrayexpress

Low input proteomics on FABP7 hi/low mammary luminal progenitor cells

Project description:Low input proteomics on FABP7 hi/low mammary luminal progenitor cells isolated from human patient samples

2023-12-11 | MSV000093639 | MassIVE

Bulk RNA-seq of mouse embryonic progenitor cells

Project description:Bulk RNA-seq of mouse embryonic progenitor cells

| PRJNA577709 | ENA

Mus musculus

Project description:Transcriptome profiles of mouse mammary stem cells and progenitor cells 2

| PRJNA339446 | ENA

Benary2021 - tissue dynamics of the hepato-pancreato-biliary organ system

Project description:Single cell-based studies have revealed tremendous cellular heterogeneity in stem cell and progenitor compartments, suggesting continuous differentiation trajectories with intermixing of cells at various states of lineage commitment and notable degree of plasticity during organogenesis. The hepato-pancreato-biliary organ system relies on a small endoderm progenitor compartment that gives rise to a variety of different adult tissues, including liver, pancreas, gallbladder, and extra-hepatic bile ducts. Experimental manipulation of various developmental signals in the mouse embryo underscored important cellular plasticity in this embryonic territory. This is also reflected in the existence of human genetic syndromes as well as congenital or environmentally-caused human malformations featuring multiorgan phenotypes in liver, pancreas and gallbladder. Nevertheless, the precise lineage hierarchy and succession of events leading to the segregation of an endoderm progenitor compartment into hepatic, biliary, and pancreatic structures are not yet established. Here, we combine computational modelling approaches with genetic lineage tracing to assess the tissue dynamics accompanying the ontogeny of the hepato-pancreato-biliary organ system. We show that a multipotent progenitor domain persists at the border between liver and pancreas, even after pancreatic fate is specified, contributing to the formation of several organ derivatives, including the liver. Moreover, using single-cell RNA sequencing we define a specialized niche that possibly supports such extended cell fate plasticity.

2021-07-01 | MODEL2105030001 | BioModels

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data