Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-8704

ABSTRACT: Transcriptional profiling of Adenosine receptor (AdoR) null mutant in Drosophila melanogaster imagoes

PROVIDER: E-MTAB-8704 | ExpressionAtlas | 2020-01-20

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-8704-analysis-methods.tsv	Tabular
	E-MTAB-8704-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-8704-configuration.xml	Xml
	E-MTAB-8704-percentile-ranks.tsv	Tabular
	E-MTAB-8704.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 38

Similar Datasets

E-MTAB-8699

Project description:Comparison of transcription profile of Adenosine receptor (AdoR) null mutant and adenosine transporter (ENT2) partial mutant in Drosophila melanogaster 3rd instar larvae

2020-01-20 | E-MTAB-8699 | ExpressionAtlas

AdoR

Project description:Drosophila melanogaster AdoR, Adenosine receptor, is expressed in 4 baseline experiment(s);

| FBgn0039747 | ExpressionAtlas

AdoR

Project description:Drosophila melanogaster AdoR, Adenosine receptor, is differentially expressed in 6 experiment(s);

| FBgn0039747 | ExpressionAtlas

Comparison of transcription profile of Adenosine receptor (AdoR) null mutant and adenosine transporter (ENT2) partial mutant in Drosophila melanogaster 3rd instar larvae

Project description:Dysregulation of adenosine (Ado) homeostasis has been observed in both rodent models and human patients of Huntington’s disease (HD). However, the underlying mechanisms of Ado signaling in HD pathogenesis is still unclear. In this study we examined influence of Ado signaling on Drosophila HD model. We further compared the transcription profiles of AdoR and ENT2 mutants by microarray analysis to identify a downstream target of AdoR signaling, which mediates the AdoR effects on HD pathology. Our findings have important implications for the crosstalk between Ado signaling and pathogenic effects of HD as well as other human diseases associated with polyglutamine aggregation.

2020-10-17 | E-MTAB-8699 | biostudies-arrayexpress

Transcriptional profiling of Adenosine receptor (AdoR) null mutant in Drosophila melanogaster imagoes

Project description:Dysregulation of adenosine (Ado) homeostasis has been observed in both rodent models and human patients of Huntington’s disease (HD). However, the underlying mechanisms of Ado signaling in HD pathogenesis is still unclear. In this study we examined influence of Ado signaling on Drosophila HD model. We further examined the transcription profile of AdoR mutants by microarray analysis to identified a downstream target of AdoR signaling, which mediates the AdoR effects on HD pathology. Our findings have important implications for the crosstalk between Ado signaling and pathogenic effects of HD as well as other human diseases associated with polyglutamine aggregation.

2020-10-17 | E-MTAB-8704 | biostudies-arrayexpress

Project description:Study on the adenosine receptor ador-1 gene of Caenorhabditis elegans

| PRJNA821643 | ENA

[E-MTAB-214] ChiP-seq profiling of Drosophila melanogaster salivary glands to identify targets for NSL1 and MCRS2.

Project description:ChiP-seq profiling of Drosophila melanogaster salivary glands to identify targets for NSL1 and MCRS2. ArrayExpress Release Date: 2010-04-16 Publication Title: The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila Publication Author List: Raja SJ, Charapitsa I, Conrad T, Vaquerizas JM, Gebhardt P, Holz H, Kadlec J, Fraterman S, Luscombe NM, Akhtar A. Person Roles: submitter Person Last Name: Vaquerizas Person First Name: Juan Person Mid Initials: M Person Email: jvaquerizas@ebi.ac.uk Person Phone: Person Address: Person Affiliation: EBI

2010-12-04 | GSE25709 | GEO

E-GEOD-15325

Project description:Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts

2014-07-03 | E-GEOD-15325 | ExpressionAtlas

E-MTAB-4611

Project description:Transcription profiling of Drosophila expressing mutant Abeta under treatment with lithium

2016-04-07 | E-MTAB-4611 | ExpressionAtlas

Ecd protein interactome in Drosophila melanogaster S2 cells

Project description:Identification of the interaction partners of the protein ecdysoneless (Ecd) in Drosophila melanogaster S2 cells as well as profiling of the changes in binding for mutant, truncated Ecd del34 protein.

2021-09-09 | PXD019838 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data