Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-PROT-40

ABSTRACT: Human colon biopsies (healthy and Ulcerative Colitis) LC-MS/MS

PROVIDER: E-PROT-40 | ExpressionAtlas | 2022-01-07

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-PROT-40-analysis-methods.tsv	Tabular
	E-PROT-40-configuration.xml	Xml
	E-PROT-40-factors.xml	Xml
	E-PROT-40-zoomifications-log.tsv	Tabular
	E-PROT-40.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 11

Similar Datasets

E-GEOD-65114

Project description:Microarray analysis of colonic mucosal biopsies from healthy controls and patients with active ulcerative colitis

2025-01-24 | E-GEOD-65114 | ExpressionAtlas

E-GEOD-6731

Project description:Transcription profiling by array of human colon biosies from patients with Crohn's disease and ulcerative colitis

2025-01-24 | E-GEOD-6731 | ExpressionAtlas

Embark cross-sectional study of inactive and active lesions from the ileum and colon of inflammatory bowel disease patients

Project description:Hypothesis: Gene expression differences in biopsies from patients with inflammatory bowel disease can be used to identify molecular heterogeneity within patients with active disease. Methods: Patients with a diagnosis of Crohn's disease, ulcerative colitis or normal healthy controls (with or without infectious colitis) underwent ileocolonoscopy. In healthy controls, biopsies were taken in the sigmoid colon (n=21), ascending/descending colon (n=25) and the terminal ileum (n=12). In patients with Crohn's disease, biopsies were taken in the ascending/descending colon (n=107) and terminal ileum (n=70) in uninflamed areas in all patients; in patients with mucosal lesions, additional biopsies were taken in inflamed regions of the ascending/descending colon (n=35) and terminal ileum (n=55). In ulcerative colitis patients, paired uninflamed sigmoid (n=48) and inflamed sigmoid biopsies (n=46) were taken. Biopsies were placed in RNAlater at the clinical site, frozen and shipped to Genentech, where they were disrupted using TissueLyzer beads, then RNA was isolated using RNeasy columns. RNA was hybridized to Agilent human 4x44kv1 arrays, dual channel, using universal reference.

2021-07-26 | GSE179285 | GEO

Gene expression profiles in sigmoid colon biopsies from healthy and patients with ulcerative colitis

Project description:Gene expression profiles were performed to compare the difference in sigmoid colon biopsies between from healthy control and patients with ulcerative colitis. Keywords: disease signature

2009-03-02 | GSE10791 | GEO

Colon biopsies from UC patients and healthy controls

2008-06-17 | GSE11223 | GEO

Colon biopsies from UC patients and healthy controls

Project description:Transcriptional profiling of colon epithelial biopsies from ulcerative colitis patients and healthy control donors. Study aims to survey and analyze variation from disease in different GI regions. Keywords: disease state analysis Biopsies from a variety of anatomic locations, from patients of various treatment status or healthy controls.

2008-06-17 | E-GEOD-11223 | biostudies-arrayexpress

E-MTAB-7860

Project description:RNA-seq of biopsies, crypts and organoids of inflamed and non-inflamed biopsies of ulcerative colitis patients

2025-01-23 | E-MTAB-7860 | ExpressionAtlas

MiRNA Profiling of Colon Tissue by Next Generation Sequencing

Project description:Ulcerative Colitis is an autoimmune inflammatory bowel disease that causes chronic inflammation in the colon and the rectum. Althoung extensively researched, the underlying molecular mechanisms of Ulcerative Colitis remain elusive. Especially, there is a lack of understanding about regulatory non-coding miRNA expression during Ulcerative Colitis. Therefore, we performed high-throughput miRNA profiling of colon tissue biopsies from XX patients with active Ulcerative Colitis, XX patients with quiescent Ulcerative Colitis and XX Symptomatic Control individuals.

2023-12-31 | GSE185102 | GEO

MiRNA Profiling of Colonic Epithelial Cell Populations by Next Generation Sequencing

Project description:Ulcerative Colitis is an autoimmune inflammatory bowel disease that causes chronic inflammation in the colon and the rectum. Althoung extensively researched, the underlying molecular mechanisms of Ulcerative Colitis remain elusive. Especially, there is a lack of understanding about regulatory non-coding miRNA expression during Ulcerative Colitis in a cell type-specific context. Therefore, we performed high-throughput miRNA profiling of Fluorescence Activated Cell Sorting (FACS)-enriched CD66a+ and CD44+ colonic epithelial cell populations from colon tissue biopsies of 16 patients with active Ulcerative Colitis, 15 patients with quiescent Ulcerative Colitis and 17 Symptomatic Control individuals.

2023-12-31 | GSE185101 | GEO

E-PROT-106

Project description:Global proteome analysis of paired colorectal cancer sample using LC-MS/MS

2023-06-22 | E-PROT-106 | ExpressionAtlas