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Goldbeter1995_CircClock

ABSTRACT: To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

SUBMITTER: Nicolas Le Novère  

PROVIDER: BIOMD0000000016 | BioModels | 2024-09-02

REPOSITORIES: BioModels

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Dataset's files

Source:
Action DRS
BIOMD0000000016?filename=BIOMD0000000016-biopax2.owl Owl
BIOMD0000000016?filename=BIOMD0000000016-biopax3.owl Owl
BIOMD0000000016?filename=BIOMD0000000016-matlab.m Other
BIOMD0000000016?filename=BIOMD0000000016-octave.m Other
BIOMD0000000016?filename=BIOMD0000000016.m Other
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Publications

A model for circadian oscillations in the Drosophila period protein (PER).

Goldbeter A A  

Proceedings. Biological sciences 19950901 1362

The mechanism of circadian oscillations in the period protein (PER) in Drosophila is investigated by means of a theoretical model. Taking into account recent experimental observations, the model for the circadian clock is based on multiple phosphorylation of PER and on the negative feedback exerted by PER on the transcription of the period (per) gene. This minimal biochemical model provides a molecular basis for circadian oscillations of the limit cycle type. During oscillations, the peak in per  ...[more]

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