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Hansen2019 - Seven species reduced model of blood coagulation

ABSTRACT: its a seven species reduced model of Hockin 2002. Model uses different level of reduction (5,7,9,11) and testing the best alignment with Hockin model results).

SUBMITTER: Krishna Kumar Tiwari

PROVIDER: MODEL1907180003 | BioModels | 2019-07-18

REPOSITORIES: BioModels

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			Action	DRS
	MODEL1907180003?filename=reduced_seven_species.cps	Other
	MODEL1907180003?filename=reduced_seven_species.sedml	Other
	MODEL1907180003?filename=reduced_seven_species.xml	Xml

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Publications

Automated reduction of blood coagulation models.

Hansen Kirk B KB Shadden Shawn C SC

International journal for numerical methods in biomedical engineering 20190829 10

Mathematical modeling of thrombosis typically involves modeling the coagulation cascade. Models of coagulation generally involve the reaction kinetics for dozens of proteins. The resulting system of equations is difficult to parameterize, and its numerical solution is challenging when coupled to blood flow or other physics important to clotting. Prior research suggests that essential aspects of coagulation may be reproduced by simpler models. This evidence motivates a systematic approach to mode ...[more]

PMID: 31161687

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