Dataset Information

Koeller2021 - PBPK model of ICG liver function tests

ABSTRACT: Physiollogically based pharmacokinetic (PBPK) model of indocyanine-green (ICG) liver function tests.

SUBMITTER: Matthias König

PROVIDER: MODEL2301090001 | BioModels | 2023-01-18

REPOSITORIES: BioModels

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Dataset's files

Source:

			Action	DRS
	MODEL2301090001?filename=icg_body.xml	Xml
	MODEL2301090001?filename=icg_body_flat.png	Other
	MODEL2301090001?filename=icg_body_flat.xml	Xml
	MODEL2301090001?filename=icg_liver.png	Other
	MODEL2301090001?filename=icg_liver.xml	Xml

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Publications

Prediction of Survival After Partial Hepatectomy Using a Physiologically Based Pharmacokinetic Model of Indocyanine Green Liver Function Tests.

Köller Adrian A Grzegorzewski Jan J Tautenhahn Hans-Michael HM König Matthias M

Frontiers in physiology 20211122

The evaluation of hepatic function and functional capacity of the liver are essential tasks in hepatology as well as in hepatobiliary surgery. Indocyanine green (ICG) is a widely applied test compound that is used in clinical routine to evaluate hepatic function. Important questions for the functional evaluation with ICG in the context of hepatectomy are how liver disease such as cirrhosis alters ICG elimination, and if postoperative survival can be predicted from preoperative ICG measurements. ...[more]

PMID: 34880771

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