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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Helicobacter pylori bearing FliK mutation to investigate the effect of the mutation on expression of eI?54 sigma factor RpoN in Helicobacter pylori

ABSTRACT: Data is also available from http://bugs.sgul.ac.uk/E-BUGS-78

ORGANISM(S): Helicobacter pylori

SUBMITTER:

PROVIDER: E-BUGS-78 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effect of FliK mutation on the transcriptional activity of the {sigma}54 sigma factor RpoN in Helicobacter pylori.

Douillard Francois P FP Ryan Kieran A KA Hinds Jason J O'Toole Paul W PW

Microbiology (Reading, England) 20090421 Pt 6

Helicobacter pylori is a motile Gram-negative bacterium that colonizes and persists in the human gastric mucosa. The flagellum gene regulatory circuitry of H. pylori is unique in many aspects compared with the Salmonella/Escherichia coli paradigms, and some regulatory checkpoints remain unclear. FliK controls the hook length during flagellar assembly. Microarray analysis of a fliK-null mutant revealed increased transcription of genes under the control of the sigma(54) sigma factor RpoN. This sig ...[more]

PMID: 19383688

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