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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling by array of Helicobacter pylori HP0256 mutants

ABSTRACT: Data is also available from BuG@Sbase

ORGANISM(S): Helicobacter pylori

SUBMITTER:

PROVIDER: E-BUGS-98 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori.

Douillard François P FP Ryan Kieran A KA Lane Michael C MC Caly Delphine L DL Moore Stanley A SA Penn Charles W CW Hinds Jason J O'Toole Paul W PW

BMC microbiology 20100408

<h4>Background</h4>Helicobacter pylori is the causative agent for gastritis, and peptic and duodenal ulcers. The bacterium displays 5-6 polar sheathed flagella that are essential for colonisation and persistence in the gastric mucosa. The biochemistry and genetics of flagellar biogenesis in H. pylori has not been fully elucidated. Bioinformatics analysis suggested that the gene HP0256, annotated as hypothetical, was a FliJ homologue. In Salmonella, FliJ is a chaperone escort protein for FlgN and ...[more]

PMID: 20377912

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