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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Helicobacter pyloric wild type and hp0958 knock-out to investigate post-transcriptional regulation of flagellin synthesis by the RpoN chaperone HP0958

ABSTRACT: Data is also available from http://bugs.sgul.ac.uk/E-BUGS-73

ORGANISM(S): Helicobacter pylori

SUBMITTER:

PROVIDER: E-BUGS-73 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Posttranscriptional regulation of flagellin synthesis in Helicobacter pylori by the RpoN chaperone HP0958.

Douillard Francois P FP Ryan Kieran A KA Caly Delphine L DL Hinds Jason J Witney Adam A AA Husain Sarah E SE O'Toole Paul W PW

Journal of bacteriology 20081017 24

The Helicobacter pylori protein HP0958 is essential for flagellum biogenesis. It has been shown that HP0958 stabilizes the sigma(54) factor RpoN. The aim of this study was to further investigate the role of HP0958 in flagellum production in H. pylori. Global transcript analysis identified a number of flagellar genes that were differentially expressed in an HP0958 mutant strain. Among these, the transcription of the major flagellin gene flaA was upregulated twofold, suggesting that HP0958 was a n ...[more]

PMID: 18931105

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