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Transcription profiling of mouse extraocular, masticatory, and hindlimb muscles to compare putative muscle allotypes


ABSTRACT: Extraocular Muscle is Defined by a Fundamentally Distinct Gene Expression Profile. Adult mouse extraocular, masticatory, and hindlimb (gastrocnemius/soleus) muscles of adult mice were compared using Affymetrix microarrays. Data form part of publication: Proceedings of the National Academy of Sciences USA 98:12062-12067, 2001.

ORGANISM(S): Mus musculus

SUBMITTER: Henry Kaminski 

PROVIDER: E-GEOD-1062 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Extraocular muscle is defined by a fundamentally distinct gene expression profile.

Porter J D JD   Khanna S S   Kaminski H J HJ   Rao J S JS   Merriam A P AP   Richmonds C R CR   Leahy P P   Li J J   Andrade F H FH  

Proceedings of the National Academy of Sciences of the United States of America 20010925 21


Skeletal muscle fibers are defined by patterned covariation of key traits that determine contractile and metabolic characteristics. Although the functional properties of most skeletal muscles result from their proportional content of a few conserved muscle fiber types, some, typically craniofacial, muscles exhibit fiber types that appear to lie outside the common phenotypic range. We analyzed gene expression profiles of three putative muscle classes, limb, masticatory, and extraocular muscle (EO  ...[more]

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