Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of mouse line with high fertiliy by microarray analysis and qPCR.


ABSTRACT: The objective of the present study was to identify genes that are involved in increasing the ovulation number in mouse line FL1 that had been selected for high fertility performance. Experiment Overall Design: Ovaries from 30 animals of line FL1 and of the control line DUKsi were collected at the metestrous stage, combined to 6 pools each, and processed for microarray analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Jens Vanselow 

PROVIDER: E-GEOD-11113 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Expression profiling of a high-fertility mouse line by microarray analysis and qPCR.

Vanselow Jens J   Nürnberg Gerd G   Koczan Dirk D   Langhammer Martina M   Thiesen Hans-Jürgen HJ   Reinsch Norbert N  

BMC genomics 20080627


<h4>Background</h4>In a recent study it was demonstrated that a largely increased ovulation number is responsible for high prolificacy in two mouse lines selected for fertility performance. The objective of the present study was to identify genes that are involved in increasing the ovulation number in one of these lines, FL1. For differential expression profiling, ovaries of FL1 and of a non-selected control line, DUKsi, both lines derived from the same genetic pool, were analyzed with microarra  ...[more]

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