Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Bekim Sadikovic
PROVIDER: E-GEOD-11414 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Sadikovic Bekim B Yoshimoto Maisa M Al-Romaih Khaldoun K Maire Georges G Zielenska Maria M Squire Jeremy A JA
PloS one 20080730 7
Genetic and epigenetic changes contribute to deregulation of gene expression and development of human cancer. Changes in DNA methylation are key epigenetic factors regulating gene expression and genomic stability. Recent progress in microarray technologies resulted in developments of high resolution platforms for profiling of genetic, epigenetic and gene expression changes. OS is a pediatric bone tumor with characteristically high level of numerical and structural chromosomal changes. Furthermor ...[more]