Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Shane Duggan
PROVIDER: E-GEOD-13400 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Duggan Shane P SP Behan Fiona M FM Kirca Murat M Smith Sinead S Reynolds John V JV Long Aideen A Kelleher Dermot D
Carcinogenesis 20100205 5
Reflux of gastroduodenal contents and consequent inflammatory responses are associated with the development of Barrett's oesophagus (BO) and the promotion of oesophageal adenocarcinoma (OAC). Deregulation of inflammatory processes is a hallmark of oesophageal cancer. In this study, we aimed to investigate (i) the transcriptional responses to deoxycholic acid (DCA) in cell lines representative of either end of the oesophageal cancer sequence, (ii) the expression of DCA-regulated genes in data cha ...[more]