Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

44 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Global survey of miRNA profiles in the uterus and an estrogen receptor alpha knockout embryo

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE13858: Global survey of miRNA microarray of uterus, ovariectomized female mice with or without estrogen (E2) treatment GSE13859: Global survey of miRNA microarray of whole embryo, wild type vs estrogen receptor alpha knockout mice Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: kaoru yamagata

PROVIDER: E-GEOD-14031 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Global survey of miRNA microarray of uterus, ovariectomized female mice with or without estrogen (E2) treatment

Project description:To examine the effect of E2 treatment for the miRNA expression, at 15 week old, female wiled type mice were ovariectomized, and after one week, estradiol (E2) was delivered at a concentration of 0.050 mg/kg body weight/day. 24 hours after chemical treatment, uteruses from mice treated with or without E2 were dissected. Two group experiment (WT-OVX and WT-OVX-E2) three replicates per condition

2010-06-24 | E-GEOD-13858 | biostudies-arrayexpress

Global survey of miRNA microarray of whole embryo, wild type vs estrogen receptor alpha knockout mice

Project description:To examine the effect of estrogen receptor alpha for the miRNA expression, total RNA extracted from whole embryos at E18.5 of wild type and Estrogen Receptor alpha knock-out mice Two group experiment (wild type and ER alpha KO)

2010-06-24 | E-GEOD-13859 | biostudies-arrayexpress

Global survey of miRNA microarray of MCF-7 cells with or without estrogen (E2) treatment

Project description:To examine the effect of E2 treatment for the miRNA expression in human MCF-7 cells, MCF-7 cells were treated with or without E2 (100 nM) for 4 hr or 24 hr. Four group experiments; E2 (100 nM) treatment for 4 hr (MCF-7 E2 4h_1, MCF-7 E2 4h_2), vehicle (ethanol) treatment for 4 hr as Mock control (MCF-7 Mock1, MCF-7 Mock2), E2 (100 nM) treatment for 24 hr (MCF-7 E2 24h_1, MCF-7 E2 24h_2, MCF-7 E2 24h_3), vehicle treatment for 24 hr as Mock control (MCF-7 Mock_3, MCF-7 Mock_4, MCF-7 Mock_5).

2010-05-15 | E-GEOD-16737 | biostudies-arrayexpress

MicroRNA profiling of wild type and p72 knock-out mice embryos

Project description:To examine the effect of DEAD-box RNA helicase subunits on the primary miRNAs processing by Drosha complex, we made knockout mice of p72, DEAD-box RNA helicase, a component of Drosha complex. And we compare the miRNA expression profiles derived from whole mice embryo between wild-type and p72 KO mice.

2007-04-12 | E-MEXP-1052 | biostudies-arrayexpress

Lactococcus lactis MG1363 â??guaA versus L. lactis MG1363 (wt)

Project description:Gene expression in Lactococcus lactis MG1363 was compared to that of L. lactis MG1363 â??guaA in rich GM17 medium. One condition design comparison of two strains

2016-01-12 | E-GEOD-76764 | biostudies-arrayexpress

Transcription profiling of human fibroblasts and keratinocytes after 125IUdR-elicited radiation treatment

Project description:Effects of 125IUdR-elicited radiation on global gene expression changes in normal human cells. This experiment uses a balanced block design where each array compares a biologically independent sample from each class (treated versus untreated)

2007-04-01 | E-MEXP-929 | biostudies-arrayexpress

Murine Bone Marrow Macrophages: Control vs. RANKL Stimulated

Project description:To identify the microRNAs that are involved in osteoclastogenesis, microRNA expression profiles in mouse bone marrow macrophages (BMMs) stimulated with RANKL (BMOc) were compared with that of control untreated BMMs. These results provide insights into the mechanisms to regulate osteoclastogenesis and bone resorption activities in osteoclasts by microRNA. BMMs were cultured with 20 ng/ml M-CSF in the presence or absence of 50 ng/ml RANKL for 24 hours. Cells were collected for total RNA isolation, and were subjected to microRNA array analysis.

2013-07-10 | E-GEOD-48629 | biostudies-arrayexpress

Microarray-based comparative genomic profiling of reference strains of Actinobacillus pleuropneumoniae

Project description:Microarray-based comparative genomic hybridizations were used to estimate whole genomic diversity of representative Actinobacillus pleuropneumoniae strains. Our goal was to identify conserved genes, especially those predicted to encode outer membrane proteins and lipoproteins because of their potential for the development of more effective vaccines. Keywords: Comparative Genomic Hybridisation Microarray data for 15 known serotypes of Actinobacillus pleuropneumoniae (at least 2 replicates per serotype).

2009-02-02 | E-GEOD-11921 | biostudies-arrayexpress

Transcription profiling of mouse poloxamer P-407 chronic hyperlipidemia mouse model

Project description:We performed a systemic study of the poloxamer P-407-induced chronic hyperlipidemia in C57BL/6J mice. Mice were treated 96 days every third day.The poloxamer mostly elevates plasma triglycerides and cholesterol while change of the liver cholesterol is not significant. Experiment Overall Design: A group of 12 mice were administered 0.5 g/kg poloxamer P-407 by intraperitoneal (i.p.) injection (poloxamere group), a control group of 4 mice were injected every third day with normal saline. Total RNA from P-407 treated 12 mice has been pooled into 3 biological replicas (Smpl1, Smpl2 and Smpl3). Reference total RNA has been obtained by pooling 4 mice from control group. Each RNA sample has been splitted and hybridised in parallel on cDNA (G4104A) and oligonucleotide (G4120A) mouse microarrays (Agilent Technologies, CA, USA.

2008-06-14 | E-GEOD-6305 | biostudies-arrayexpress

L. lactis MG1363 transcriptome analysis of 4 evolved strains

Project description:L. lactis MG1363 was evolved in 4 fermentors in glucose-containing chemically defined medium (CDMPC) for 309 generations at a dilution rate of 0.5h-1 Glycerol stocks made during the evolution experiment were revived in CDMPC and further characterized. Glycerol stocks from generation 309 were revived in CDMPC and grown to mid-exponential phase. Strains from each of the 4 fermentors were compared to the original strain (Generation 0).

2016-03-01 | E-GEOD-67657 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data