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Transcription profiling of Pseudomonas aeruginosa to investigate the toxicogenomic Effects of Chlorhexidine diacetate

ABSTRACT: In the present study, we employed Affymetrix Pseudomonas aeruginosa GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Pseudomonas aeruginosa to Chlorhexidine diacetate, which involved initial growth inhibition and metabolism. Experiment Overall Design: We conducted three independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Chlorhexidine diacetate. We calculated fold change as the ratio between the signal averages of three untreated (control) and three chlorhexidine diacetate-treated (experimental) cultures for 0, 10 and 60 min exposures.

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Chantal Wheko Nde

PROVIDER: E-GEOD-14253 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcription profiling of Pseudomonas aeruginosa treated with hydrogen peroxide

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