Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Lindsay Lovasco
PROVIDER: E-GEOD-15228 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Biology of reproduction 20090814 1
The mammalian ovary is unique in that its reproductive life span is limited by oocyte quantity and quality. Oocytes are recruited from a finite pool of primordial follicles that are usually exhausted from the ovary during midadult life. If regulation of this pool is perturbed, the reproductive capacity of the ovary is compromised. TAF4B is a gonad-enriched subunit of the TFIID complex required for female fertility in mice. Previous characterization of TAF4B-deficient ovaries revealed several rep ...[more]