Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Evie Melanitou
PROVIDER: E-GEOD-15582 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
BMC medical genomics 20091002
<h4>Background</h4>Autoimmune diabetes (T1D) onset is preceded by a long inflammatory process directed against the insulin-secreting beta cells of the pancreas. Deciphering the early autoimmune mechanisms represents a challenge due to the absence of clinical signs at early disease stages. The aim of this study was to identify genes implicated in the early steps of the autoimmune process, prior to inflammation, in T1D. We have previously established that insulin autoantibodies (E-IAA) predict ear ...[more]