Transcription profiling of aortas of mice on high fat diet
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Raymond Tabibiazar
PROVIDER: E-GEOD-1560 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.
Tabibiazar Raymond R Wagner Roger A RA Spin Joshua M JM Ashley Euan A EA Narasimhan Balasubramanian B Rubin Edward M EM Efron Bradley B Tsao Phil S PS Tibshirani Robert R Quertermous Thomas T
Arteriosclerosis, thrombosis, and vascular biology 20041118 2
<h4>Objective</h4>Different strains of inbred mice exhibit different susceptibility to the development of atherosclerosis. The C3H/HeJ and C57Bl/6 mice have been used in several studies aimed at understanding the genetic basis of atherosclerosis. Under controlled environmental conditions, variations in susceptibility to atherosclerosis reflect differences in genetic makeup, and these differences must be reflected in gene expression patterns that are temporally related to the development of disea ...[more]
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