Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: TIAN TANG
PROVIDER: E-GEOD-15851 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Proceedings of the National Academy of Sciences of the United States of America 20100706 29
It is commonly assumed but not proven that microRNAs (miRNAs) and their targets coevolve. Under this assumption, miRNAs and targets from different species may interact adversely, resulting in reduced fitness. However, the strength of the adverse interactions may not be detectable because even outright deletions of miRNAs often manifest only subtle fitness effects. We tested and measured the strength of heterospecific interactions by carrying out transgenic experiments across Drosophila species b ...[more]