Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Saccharomyces cerevisiae under serial stresses


ABSTRACT: S. cerevisae cells were exposed to different series of mild stresses. Stress type include heat shock, oxidative and osmotic stresses. Microarrays were used to follow the genome-wide transcriptional response to the stresses and to identify genes that can underlie the cross protection phenotype between heat shock and oxidative stress. Experiment Overall Design: Cell sample at different time points after stress application were used for RNA extraction and hybridization on Affymetrix microarrays.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Amir Mitchell 

PROVIDER: E-GEOD-15936 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Adaptive prediction of environmental changes by microorganisms.

Mitchell Amir A   Romano Gal H GH   Groisman Bella B   Yona Avihu A   Dekel Erez E   Kupiec Martin M   Dahan Orna O   Pilpel Yitzhak Y  

Nature 20090617 7252


Natural habitats of some microorganisms may fluctuate erratically, whereas others, which are more predictable, offer the opportunity to prepare in advance for the next environmental change. In analogy to classical Pavlovian conditioning, microorganisms may have evolved to anticipate environmental stimuli by adapting to their temporal order of appearance. Here we present evidence for environmental change anticipation in two model microorganisms, Escherichia coli and Saccharomyces cerevisiae. We s  ...[more]

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