Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Peter Walter
PROVIDER: E-GEOD-1688 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Patil Christopher K CK Li Hao H Walter Peter P
PLoS biology 20040817 8
Eukaryotic cells respond to accumulation of unfolded proteins in the endoplasmic reticulum (ER) by activating the unfolded protein response (UPR), a signal transduction pathway that communicates between the ER and the nucleus. In yeast, a large set of UPR target genes has been experimentally determined, but the previously characterized unfolded protein response element (UPRE), an upstream activating sequence (UAS) found in the promoter of the UPR target gene KAR2, cannot account for the transcri ...[more]