Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Raffaele Calogero
PROVIDER: E-GEOD-17449 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Gilli Francesca F Lindberg Raija L P RL Valentino Paola P Marnetto Fabiana F Malucchi Simona S Sala Arianna A Capobianco Marco M di Sapio Alessia A Sperli Francesca F Kappos Ludwig L Calogero Raffaele A RA Bertolotto Antonio A
PloS one 20100129 1
<h4>Background</h4>Pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood.<h4>Methodology</h4>We conducted a genome-wide transcription analysis in peripheral blood mononuclear cells (PBMCs) from 12 women (7 MS patients and 5 healthy controls) followed during their pregnancy. Samples were obtained before, during (i.e. at the third, sixth, and ninth month of ge ...[more]