Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Rita Vassena
PROVIDER: E-GEOD-17886 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Han Zhiming Z Mtango Namdori R NR Zhong Zhisheng Z Vassena Rita R Latham Keith E KE
American journal of physiology. Cell physiology 20100127 5
Blastomere cytofragmentation in mammalian embryos poses a significant problem in applied and clinical embryology. Mouse two-cell-stage embryos display strain-dependent differences in the rate of cytofragmentation, with a high rate observed in C3H/HeJ embryos and a lower rate observed in C57BL/6 embryos. The maternally inherited genome exerts the strongest effect on the process, with lesser effects mediated by the paternally inherited genome and the ooplasm. The effect of the maternal genome is t ...[more]