CHIP Analysis - c-Jun/ATF2
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Eileen Adamson
PROVIDER: E-GEOD-1810 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress.
Hayakawa Jun J Mittal Shalu S Wang Yipeng Y Korkmaz Kemal S KS Adamson Eileen E English Christopher C Ohmichi Masahide M McClelland Michael M Mercola Dan D
Molecular cell 20041101 4
The NH2-terminal Jun kinases (JNKs) function in diverse roles through phosphorylation and activation of AP-1 components including ATF2 and c-Jun. However, the genes that mediate these processes are poorly understood. A model phenotype characterized by rapid activation of Jun kinase and enhanced DNA repair following cisplatin treatment was examined using chromatin immunoprecipitation with antibodies against ATF2 and c-Jun or their phosphorylated forms and hybridization to promoter arrays. Followi ...[more]
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