Nucleases Encoded by Integrated Elements CJIE2 and CJIE4 Inhibit Natural Transformation of Campylobacter jejuni
Ontology highlight
ABSTRACT:
ORGANISM(S): Campylobacter jejuni
SUBMITTER: Jos van Putten
PROVIDER: E-GEOD-18399 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Nucleases encoded by the integrated elements CJIE2 and CJIE4 inhibit natural transformation of Campylobacter jejuni.
Gaasbeek Esther J EJ Wagenaar Jaap A JA Guilhabert Magalie R MR van Putten Jos P M JP Parker Craig T CT van der Wal Fimme J FJ
Journal of bacteriology 20091218 4
The species Campylobacter jejuni is naturally competent for DNA uptake; nevertheless, nonnaturally transformable strains do exist. For a subset of strains we previously showed that a periplasmic DNase, encoded by dns, inhibits natural transformation in C. jejuni. In the present study, genetic factors coding for DNase activity in the absence of dns were identified. DNA arrays indicated that nonnaturally transformable dns-negative strains contain putative DNA/RNA nonspecific endonucleases encoded ...[more]
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