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Transcription profiling of livers from mice fed control diet or diets supplemented with 1% Fraction 1 (haxane) or Fraction 2 (methanol) of Boswellia Serrata.

ABSTRACT: Hepatic gene expression analysis in mice fed control diet or diets supplemented with 1% Fraction 1 (haxane) or Fraction 2 (methanol) of Boswellia Serrata.

ORGANISM(S): Mus musculus

SUBMITTER: Pawel Kiela

PROVIDER: E-GEOD-1847 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effects of Boswellia serrata in mouse models of chemically induced colitis.

Kiela Pawel R PR Midura Anna J AJ Kuscuoglu Nesrin N Jolad Shivanand D SD Sólyom Anikó M AM Besselsen David G DG Timmermann Barbara N BN Ghishan Fayez K FK

American journal of physiology. Gastrointestinal and liver physiology 20041111 4

Extracts from Boswellia serrata have been reported to have anti-inflammatory activity, primarily via boswellic acid-mediated inhibition of leukotriene synthesis. In three small clinical trials, boswellia was shown to improve symptoms of ulcerative colitis and Crohn's disease, and because of its alleged safety, boswellia was considered superior over mesalazine in terms of a benefit-risk evaluation. The goal of this study was to evaluate the effectiveness of boswellia extracts in controlled settin ...[more]

PMID: 15539433

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