Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ute Ungethuem
PROVIDER: E-GEOD-1919 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Ungethuem U U Haeupl T T Witt H H Koczan D D Krenn V V Huber H H von Helversen T M TM Drungowski M M Seyfert C C Zacher J J Pruss A A Neidel J J Lehrach H H Thiesen H J HJ Ruiz P P Bläss S S
Physiological genomics 20100921 4
Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease of unknown etiology and pronounced interpatient heterogeneity. To characterize RA at the molecular level and to uncover pathomechanisms, we performed genome-wide gene expression analysis. We identified a set of 1,054 genes significantly deregulated in pair-wise comparisons between RA and osteoarthritis (OA) patients, RA and normal donors (ND), or OA and ND. Correlation analysis revealed gene sets regulated identically in all thre ...[more]