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Transcription profiling of mouse FACS purified cortical projection neurons

ABSTRACT: 3 subtypes of cortical projection neurons were purified by fluorescence-activated cell sorting at 4 different stages of development from mouse cortex. A detailed description of the data set is described in Arlotta, P et al (2005)

ORGANISM(S): Mus musculus

SUBMITTER: Bradley Molyneaux

PROVIDER: E-GEOD-2039 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.

Arlotta Paola P Molyneaux Bradley J BJ Chen Jinhui J Inoue Jun J Kominami Ryo R Macklis Jeffrey D JD

Neuron 20050101 2

Within the vertebrate nervous system, the presence of many different lineages of neurons and glia complicates the molecular characterization of single neuronal populations. In order to elucidate molecular mechanisms underlying the specification and development of corticospinal motor neurons (CSMN), we purified CSMN at distinct stages of development in vivo and compared their gene expression to two other pure populations of cortical projection neurons: callosal projection neurons and corticotecta ...[more]

PMID: 15664173

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