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Leucine starvation series

ABSTRACT: These data represent the ratios of charged to total tRNA for E. coli auxotrophic strain CP78 during starvation for leucine over a time course of 32 minutes.

ORGANISM(S): Escherichia coli

SUBMITTER: Kimberly Dittmar

PROVIDER: E-GEOD-2065 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Selective charging of tRNA isoacceptors induced by amino-acid starvation.

Dittmar Kimberly A KA Sørensen Michael A MA Elf Johan J Ehrenberg Måns M Pan Tao T

EMBO reports 20050201 2

Aminoacylated (charged) transfer RNA isoacceptors read different messenger RNA codons for the same amino acid. The concentration of an isoacceptor and its charged fraction are principal determinants of the translation rate of its codons. A recent theoretical model predicts that amino-acid starvation results in 'selective charging' where the charging levels of some tRNA isoacceptors will be low and those of others will remain high. Here, we developed a microarray for the analysis of charged fract ...[more]

PMID: 15678157

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Leucine starvation series

Project description:These data represent the ratios of charged to total tRNA for E. coli auxotrophic strain CP78 during starvation for leucine over a time course of 32 minutes. Keywords: time-course

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