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Effect of loss of Gfi1b on hematopietic stem cells

ABSTRACT: Using Gfi1b conditional mice, deletion of gfi1b in the hematopietic system was induced by injecting MxCre tg Gfi1bfl/fl mice with pIpC. 30 days after injection, Cd150 pos, Cd 48 neg, Lin neg Sca and c-kit pos stem cells were sortrted from Gfi1bfl/fl and Mxcre tg Gfi1bfl/fl mice and analysed. We used the mouse Affymetrix Gene ST Array. The study should determine whether loss of Gfi1 alters the gene expression pattern in the hematopietic stem cells.

ORGANISM(S): Mus musculus

SUBMITTER: Tarik Moroy

PROVIDER: E-GEOD-20655 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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