Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: yewei xing
PROVIDER: E-GEOD-20676 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Xing Yewei Y Parker C Richard CR Edwards Michael M Rainey William E WE
Journal of molecular endocrinology 20100511 1
The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so-called adrenal androgens. Under physiological conditions, cortisol and adrenal androgen synthesis are controlled primarily by ACTH. Although it has been established that ACTH can stimulate steroidogenesis, the effects of ACTH on overall gene expression in human adrenal cells have not been established. In this study, we defined the effects of chronic ACTH treatment on global gene expression in primary cultu ...[more]