Systematic analysis of miRNA transcriptome of skeletal muscle identifies novel miRNAs and differentially expressed miRNAs in divergent skeletal muscle growth rates of broiler and layer chickens
Ontology highlight
ABSTRACT:
ORGANISM(S): Gallus gallus
SUBMITTER: Tingting Li
PROVIDER: E-GEOD-20992 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAs.
Li Tingting T Wu Rimao R Zhang Yong Y Zhu Dahai D
BMC genomics 20110413
<h4>Background</h4>Functional studies have demonstrated that microRNAs (miRNAs or miRs) play critical roles in a wide spectrum of biological processes including development and disease pathogenesis. To investigate the functional roles that miRNAs play during chicken skeletal muscle development, the miRNA transcriptomes of skeletal muscles from broiler and layer chickens were profiled using Solexa deep sequencing.<h4>Results</h4>Some miRNAs have multiple isoforms and several miRNAs* are present a ...[more]
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