Unknown,Transcriptomics,Genomics,Proteomics

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Identification of miRNAs involved in embyonic chicken muscle development


ABSTRACT: In the current study, we expanded our previous work to identify miRNAs implicated in the myogenesis regulation through the comparison of miRNAs transcriptome in skeletal muscle tissues between broilers and layers. miRNA expression studies of two different intra-species breeds

ORGANISM(S): Gallus gallus

SUBMITTER: Tingting Li 

PROVIDER: E-GEOD-20947 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAs.

Li Tingting T   Wu Rimao R   Zhang Yong Y   Zhu Dahai D  

BMC genomics 20110413


<h4>Background</h4>Functional studies have demonstrated that microRNAs (miRNAs or miRs) play critical roles in a wide spectrum of biological processes including development and disease pathogenesis. To investigate the functional roles that miRNAs play during chicken skeletal muscle development, the miRNA transcriptomes of skeletal muscles from broiler and layer chickens were profiled using Solexa deep sequencing.<h4>Results</h4>Some miRNAs have multiple isoforms and several miRNAs* are present a  ...[more]

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