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Global Gene Expression Profiling of Bovine Lymphocyte Populations

ABSTRACT: Gene expression profiling of pooled lymphocyte populations from clinically normal cattle. The T lymphocyte populations were purified from buffy coat and the immature B cells were prepared from isolated Peyer's patch follicles. Keywords: other

ORGANISM(S): Bos taurus

SUBMITTER: John Neill

PROVIDER: E-GEOD-2244 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Global gene expression profiling of Bovine immature B cells using serial analysis of gene expression.

Neill John D JD Ridpath Julia F JF Liebler-Tenorio Elizabeth E

Animal biotechnology 20060101 1

The Peyer's patches of the small intestine are important sites of antigen processing. The follicles of the Peyer's patches receive the antigen transported by the M cells at the mucosal surface and then play a major role in development of both protective humoral and mucosal immune responses. Serial analysis of gene expression (SAGE) was employed to derive the global gene expression profile of B lymphocytes isolated from the IPPF. Analysis of the SAGE data revealed the identity of genes and the le ...[more]

PMID: 16621757

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